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Nexavar is indicated for the treatment of hepatocellular carcinoma. This is not a complete list of side effects and others may occur. La dose de Nexavar recommandée chez l’adulte est de 400 mg de sorafénib (2 comprimés de 200 mg) deux fois par jour (soit une dose totale journalière de 800 mg). Renal cell carcinoma Nexavar is indicated for the treatment of patients with advanced renal cell carcinoma who have failed prior interferon-alpha or interleukin-2 based therapy or are considered unsuitable for such therapy. Differentiated thyroid carcinoma. The recommended dosage of NEXAVAR is 400 mg orally twice daily without food (at least 1 hour before or 2 hours after a meal) until the patient is no longer clinically benfiting from therapy or until unacceptable toxicity. Your healthcare professional may change your dose during treatment or stop treatment for some time if you have side effects. Common Nexavar side effects may include: bleeding; feeling tired; vomiting, diarrhea, nausea, stomach pain; high blood pressure; rash; or. This may affect your ability to father a child. Treatment should continue until the patient is. La dose raccomandata di Nexavar negli adulti è di 400 mg di sorafenib (due compresse da 200 mg) due volte al giorno (equivalente a una dose totale giornaliera di 800 mg). Le traitement doit être poursuivi tant qu’un bénéfice clinique est observé ou jusqu’à la survenue d’une toxicité inacceptable. Are breastfeeding or plan to breastfeed The recommended daily dose of NEXAVAR is 2 tablets taken 2 times a day (for a total of 4 tablets each day). Take NEXAVAR without food (at least 1 hour before or 2 hours after a meal) Nexavar is indicated for the treatment of hepatocellular carcinoma. Note: In patients undergoing major surgical procedures, interrupt treatment (temporarily). Sorafenib (Nexavar) Dose in Adults. Talk to your healthcare provider if this is a concern for you. NEXAVAR may cause fertility problems in males. Continue until no longer clinically benefiting or until unacceptable toxicity occurs (Llovet 2008). Dosage Modifications for Adverse Reactions Recommended Dosage Modifications. Prescribing NEXAVAR Dosage and administration 1 The recommended daily dose is 800 mg: 400 mg taken twice daily orally (2 x 200-mg tablets) without food (at least 1 hour before or 2 hours after a meal) Tablets shown are not actual size. Nexavar is FDA-approved to treat: Hepatocellular carcinoma (HCC) Use effective birth control (contraception) during your treatment with NEXAVAR and for 3 months after the last dose of NEXAVAR. Call your doctor for medical advice about side effects If the original dose of afatinib is not tolerated, consider reducing the daily dose of afatinib by 10 mg; resume the previous dose of afatinib as tolerated after discontinuation of sorafenib. When dose reduction is necessary for dermatologic toxicities, reduce the NEXAVAR dose as indicated in Table 2. Il trattamento deve continuare fino a quando si osserva un beneficio clinico, o finché non compaiono tossicità inaccettabili. Sorafenib (Nexavar) Dose in the treatment of Hepatocellular cancer (HCC): P/O: 400 mg twice daily. Nexavar is a brand-name prescription medication that’s used to treat certain types of liver, kidney, and thyroid cancer in adults. Learn more about Access Services by BayerTM Financial assistance. The recommended daily dose of NEXAVAR is 400 mg (2 x 200 mg tablets) taken twice daily without food (at least 1 hour before or 2 hours after a meal).
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